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山羊胎期肺的组织发生
张 涌1, 郑月茂1
西北农林科技大学 生物工程研究所
摘要:
研究了山羊胎期肺的组织发生,将肺的发育分为5个时期①胚胎期(3~5周),肺芽分支形成主支气管,主支气管长度不断增长并萌芽出叶支气管,均衬以假复层柱状上皮;②腺状期(6~12周),以支气管树发育为主,小支气管及终蕾衬以假复层和/或单层柱状上皮;③小管期(13~14周),以呼吸部发育为主,原始肺泡开始形成,呼吸性细支气管和原始肺泡衬以未分化的立方上皮;④囊状期(第15周),呼吸部发育显著,肺内细支气管及其末端呈现出“充气”状态;⑤肺泡期(16~22周),以肺泡的形成和分化为主,肺泡上皮分化为扁平的肺泡Ⅰ型细胞和立方形的肺泡Ⅱ型细胞。
关键词:  胎期肺  组织发生  山羊
DOI:
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基金项目:国自然科学基金资助项目(39830280)
Histogenesis of the goat lung
Abstract:
50 goat embryoes and/or fetal lungs were observed with LM which showed the embryologic,pseudoglandular,canalicular,saccular and alveolar stages during their development.1.Embryologic stage(3-5wks):The lung bud branching and forming into the two principal bronchi,the principal bronchi growing in length and budding lobar bronchi lined with seudostratified columnar epithelium.2.Pseudoglandular stage(6-12wks):The bronchial divisions were differentiated and their air conduction system became established,lined with seudostratified and/or single-walled colummar conducting epithelium.3.Canalicular stage(13-14wks):The respiratory bronchioles developed quickly,the primitive alveoli had developed,the respiratory bronchioles and primitive alveoli were lined by cuboid cells.4.Saccular stage(15wk):The respiratory divisions developed dramatically,the lung assumed a more “aeraated”appearance.5.Alveolar stage(16-22wks):The alveoli developed and differentiated into flattened (typeⅠcell)and cuboid(typeⅡcell)epithelial cells.
Key words:  embryoes/fetal lung  histogenesis  goat

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