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新三唑类化合物的合成及抑菌活性研究
周文明1, 王昌钊1, 李长杰2
1.西北农林科技大学 生命科学学院;2.莱阳畜牧局
摘要:
以3,3-二甲基-1-(1,2,4-三唑-1-基)-2-丁酮为原料,合成了6个新化合物,化合物的结构均经1H-NMR和IR予以确认。以小麦赤霉病菌(Fusarium graminearum)、苹果炭疽病菌(Glomerella cingulata)、玉米大斑病菌(Exserohilum turcium)及南瓜枯萎病菌(Fusarium oxysporium)为供试菌种,在100 μg/mL质量浓度下,对合成化合物进行了杀菌活性测定,结果表明6种化合物均有不同程度的杀菌活性。
关键词:  三唑类化合物  合成  杀菌活性
DOI:
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基金项目:西北农林科技大学校青年基金项目(KD00-56)
Synthesization and fungicidal activities of new triazole compounds
Abstract:
Six new compounds were synthesized from 3,3-dimethyl-1-(1,2,4-trizole-1-yl)-butanone,and their biological activities were studied.The structures of all the compounds were confirmed by means of 1H-NMR and IR.The preliminary bioassays results showed that all the new compounds exhibited certain fungicidal activities against Fusarium oxysporium,Glomerella cingulata,Fusarium graminearum and Exserohilum turcium in 100 μg/mL.
Key words:  triazole compounds  organic synthesis  fungicidal activity

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