| 摘要: |
| 应用从猪红细胞提取的CD58分子协同新城疫Ⅳ疫苗，免疫18日龄尼克红公鸡，以β－微量法测定ND抗体效价，并在免疫后39d用F48ECD9强毒株攻毒，结果表明，CD58能促进ND抗体的提前产生，使应答负期明显缩短，并且试验组ND抗体效价显著高于对照组（P＜0.05或P＜0.01）。攻毒后7 d 内，试验组鸡死亡率为16.7％，对照组为53.3％。 |
| 关键词: CD58分子 新城疫Ⅳ疫苗 抗体测定 攻毒试验 |
| DOI： |
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| 基金项目:陕西省自然科学基金资助项目(99SM01) |
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| The adjuvani effect of CD58 on ND Ⅳ strain vaccination |
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| Abstract: |
| 18 d chicks vaccinated with newcastle disease (ND) Ⅳ strain vaccine cooporated with CD58 molecular from pig crythrocyte.The ND antibody titers were detected by using β-method.These chicks were attacked by F48ECD9 virulent strain after 39 d of inoculation.The results showed that CD58 molecular could promote ND antibody development,and the ND antibody titers of chicks in test group were strikingly higher than those of chicks in control group.In 7 d after being attacked by F48ECD9 virulent virus,the death rate of chicks in control group was 53.3% while that in test group was 16.7%. |
| Key words: CD58 molecular newcastle disease Ⅳ strain vaccine antibody test virus attacking test |
