| 摘要: |
| 【目的】研究2-芳基-6,7-亚甲二氧基-3,4-二氢异喹啉盐类化合物对植物种子发芽和幼苗生长的安全性，为此类化合物作为新型植物抗菌药物的开发应用提供理论依据。【方法】将糜子和油菜种子在14种2-芳基-6,7-亚甲二氧基 3,4-二氢异喹啉盐类化合物(Z-1～Z-14)溶液中浸种20 h后，均匀点播于含无离子水的培养皿中，在设定条件下进行培养，测定种子的发芽率、根长、茎长、总鲜质量、总干质量和相对含水量。【结果】在100 μg/mL测试质量浓度下，化合物Z-1、Z-3、Z-12、Z-13和Z-14对1种或2种作物的个别生长指标有显著的抑制作用，化合物Z-2、Z-4、Z-9和Z-10能够显著促进糜子根和茎的生长，同时对糜子的发芽率和幼苗的相对含水量没有显著影响；其他供试化合物对糜子和油菜的种子发芽和幼苗生长均无显著影响。【结论】除化合物Z-1、Z-3、Z-12、Z-13和Z-14外，其他供试的化合物在质量浓度≤100 μg/mL时，对受试作物的种子萌发和幼苗生长均不会产生不良影响，部分化合物还具有促进作物根茎生长的效果，具备进一步评测后作为作物抗菌剂开发的可能。 |
| 关键词: 异喹啉类化合物 抗菌药物 作物抗菌剂 安全性评价 |
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| 基金项目:国家自然科学基金项目(31000865，31172365，31101469) |
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| Effects of 2-aryl-3,4-dihydroisoquinolin-2-iums as antifungal agents on plant seed germination and seedling growth |
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ZHENG Zuo-lüe,MIAO Fang,YANG Xin-juan,et al
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| Abstract: |
| 【Objective】This paper investigated the effects of 2-Aryl-6,7-methylenedioxy-3,4-dihydroisoquinolin-2-ium salts on plant seed germination and seedling growth to provide theoretical basis for the development and application of such compounds as new phytofungicides.【Method】The seeds of Panicum miliaceum L.and Brassica campestris L.were soaked in the solution of 14 2-Aryl-6,7-methylenedioxy-3,4-dihydroisoquinolin-2-ium salts for 20 h before being evenly sowed in Petri dish containing a small amount of deionized water.Then they were cultured in set conditions and germination rate,average root length,stem length,gross fresh weight,gross dry weight and relative water content were determined.【Result】At 100 μg/mL,compounds Z-1,Z-3,Z-12,Z-13 and Z-14 showed significantly negative effects on some indicators of germination and growth of one or two plants.Compounds Z-2,Z-4,Z-9,and Z-10 significantly improved the roots and stems of Panicum miliaceum L.The other compounds showed no significant effects.【Conclusion】Except Z-1,Z-3,Z-12,Z-13 and Z-14,other tested compounds were safe to plants when used with mass concentrations of no higher than 100 μg/mL.Some compounds even promoted crops roots and stems,and could be developed as crop antifungal agents after further evaluation. |
| Key words: isoquinoline compounds antifungal medicines phytofungicides safety evaluation |
