| 摘要: |
| 秀丽隐杆线虫具有受机械接触、温度、化学物质、离子、外激素等多种环境刺激产生敏感反应的能力，其已被证明是研究行为可塑性的理想模式生物。文章阐述了秀丽隐杆线虫非联合型学习和联合型学习的研究方法、研究模型和相关分子遗传机制，为了解高等动物学习过程、机理及相关疾病研究提供了重要信息。 |
| 关键词: 线虫 学习行为研究方法 化学趋向性 温度趋向性 |
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| 基金项目:国家“973”计划项目(2006CB504100)；国家科技重大专项课题(2008ZXJ09014-0093)；国家自然科学基金项目(30771230，30600365)；中国博士后科学基金特别资助基金项目(200801495)；中国博士后科学基金项目(20060400051)；军事医学科学院创新基金项目 |
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| Current progress on the methods for studying learning behavior of Caenorhabditis elegans |
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LI Hua LI Yong WU Ying WANG Hua
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| Abstract: |
| The nematode Caenorhabditis elegans is an attractive model organism for studying the behavioral plasticity because of its ability to respond to diverse environmental stimuli such as touch,temperature,chemical,and pheromone.C elegans have learning ability including both non associative learning and associative learning.This review discusses the methods,models,molecular and genetic mechanisms of these two kinds of learning behaviors in Caenorhabditis elegans ,which will provide a crucial novel imformation for understanding the process,mechanism and disease related to learning. |
| Key words: Caenorhabditis elegans research method of learning behavior thermotaxis chemotaxis |
