| 摘要: |
| 选用60头质量28 kg左右的“杜长大”三元杂交猪,随机分为2组,每组3个重复,每重复10头猪(公母各半),分别饲喂基础日粮(C组)和基础日粮 0.1 mg/kg黄曲霉毒素(AF组),预试期7 d,正试期90 d,研究黄曲霉毒素对猪生长性能、内脏器官相对质量、血清和肝脏酶活性指标的影响。结果表明,黄曲霉毒素(AF)显著降低了试验猪的生长性能,AF组猪日增重降低了12.90%(P<0.01),料重比提高了7.54%(P<0.01);AF显著影响试验猪内脏器官的相对质量,AF组猪肝脏、肾脏、脾脏、胰脏的相对质量分别较C组提高了8.24%(P<0.05)、27.27%(P<0.01)、41.18%(P<0.01)、42.86%(P<0.01);AF使试验猪肝脏功能严重受损,胞内酶大量释放到血液中,AF组猪血清酶活性指标显著升高,肝脏酶活性指标显著降低。这些结果表明,长期饲喂黄曲霉毒素污染的日粮诱发了猪黄曲霉毒素的慢性中毒。 |
| 关键词: 黄曲霉毒素 猪 生长性能 肝功能 |
| DOI： |
| 分类号: |
| 基金项目:浙江省科技厅重点项目（021122680） |
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| Effects of aflatoxin on growth performance and liver function of pigs |
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| Abstract: |
| Experiments were conducted to determine the effects of aflatoxin (AF) on growth performance,relative organ weights,serum and liver enzyme activities of growing/finishing pigs.A total of 60 crossbred pigs (Duroc×Landrace×Large white) were randomly divided to two treatment groups by sex (three replicates per treatment with ten pigs per replicate).Two dietary treatments of control feed,and control feed plus 0.1 mg/kg AF were fed to pigs for 90 days.The results showed that AF had significant effects on growth performance and relative organ weights of pigs,average daily gain was decreased by 12.90%(P<0.01) and feed gain ratio was increased by 7.54% (P<0.01) in pigs fed by AF diet;relative weights of liver,kidney,spleen and pancreas were increased by 8.24％(P<0.01),27.27％(P<0.01),41.18％(P<0.01) and 42.86％(P<0.01)respectively.Furthermore,liver function was injured by AF intake and liver enzymes were leaked out into the blood with the increase of serum enzyme activities and the decrease of liver enzyme activities.These findings suggested that long term intake of AF induced chronic toxicity of AF in pigs. |
| Key words: aflatoxin,pigs,growth performance,liver function |
