| 摘要: |
| 目前发现的猪肠道冠状病毒主要有猪流行性腹泻病毒（PEDV）、猪三角冠状病毒（PDCoV）、猪传染性胃肠炎病毒（TGEV）和猪急性腹泻综合征冠状病毒（SADS-CoV）4种。其中SADS-CoV是2017年首次在我国广东省发现的一种猪肠道冠状病毒，该病毒感染后可致小于5日龄仔猪出现严重急性腹泻、急性呕吐、脱水等症状，死亡率较高，给养猪业造成巨大的经济损失。目前还未见针对SADS CoV的有效药物和疫苗产品上市，从病毒传播、致病机制、诊断及预防控制等方面综述SADS-CoV的研究进展，期望为SADS-CoV的防控提供参考。 |
| 关键词: 猪急性腹泻综合征 冠状病毒 致病机制 病毒流行 病毒防控 |
| DOI：DOI:10.13207/j.cnki.jnwafu.2024.10.004 |
| 分类号: |
| 基金项目:浙江省“三农九方”农业科技协作计划“揭榜挂帅”项目（2022SNJF060）；浙江省“领雁”研发攻关计划项目(2023C02023,2023C02047) |
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| Research progress on prevalence, pathogenesis and prevention and control of porcine acute diarrhea syndrome coronavirus |
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CHEN Mengru1, WANG Yue1, FENG Huapeng1, QUAN Yanping1, CHEN Jian1, SHU Jianhong1,2, HE Yulong1
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1.School of Life Sciences and Medicine,Zhejiang SciTech University,Hangzhou,Zhejiang 310000,China;2.Zhejiang Hongsheng Biotechnology Co.,Ltd,Shaoxing,Zhejiang 312090,China
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| Abstract: |
| The main porcine enteric coronaviruses currently discovered include porcine epidemic diarrhea virus (PEDV),porcine deltacoronavirus (PDCoV),porcine transmissible gastroenteritis virus (TGEV) and swine acute diarrhea syndrome coronavirus (SADS CoV).SADS-CoV is a porcine enteric coronavirus firstly discovered in Guangdong,China in 2017.Infection with the virus causes piglets less than 5 days old to develop symptoms such as severe acute diarrhea,acute vomiting,dehydration and high mortality,which causes huge economic losses to the pig industry.Currently,there are no effective drugs or vaccines against SADS-CoV on market.This article reviews the research progress of SADS-CoV from the aspects of virus transmission,pathogenesis,diagnosis,prevention and control,aiming to provide reference for the prevention and control of SADS-CoV. |
| Key words: porcine acute diarrhea syndrome coronavirus pathogenic mechanism epidemic prevention and control |
