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中草药添加剂抗应激反应免疫药理试验研究
贾英科1, 高梅秀1
天津农学院
摘要:
将中草药添加剂抗常规方法煎煮,制成质量浓度1 g/ml煎液,取体重19-23 g的健康小白鼠,随机分组,试验组每只每日口服煎液0.5 mL,对照组每只每日口服生理盐水0.5 mL,连续7 d,停药后检测结果表明,中草药添加剂可显著提高腹腔巨噬细胞吞噬功能(t测验P<0.01),明显增加外周血液中T,C数量(t测验0.01<P<0.05),并显著提高血清抗体水平(t测验P<0.01),因此认为,该试验所用中草药添加剂能显著增加动物机体非特异性免疫功能和特异性免疫功能。
关键词:  中草药添加剂  抗应激反应  免疫药理
DOI:
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基金项目:天津市自然科学基金资助项目(973611911)
Immunopharmacological studies of Chinese herbal additive on anti-allergic reaction
Abstract:
Several Chinese herbs including root of Chinese herbal additive were decocted in a conventional manner to be quality density 100% decoctum.Healthy mice of Kunming origin weighing 19-23 g,both male and female,were randomly divided into a treatment group and a control group.For 7 consecutive d,each of the treatment mice was poured with Chinese herbal additive decoctum every day a chicken 0.5 mL,and each of the control mice normal saline every day a chicken 0.5 mL.Percentage of phagocytosis,phagocytic index,ANAE+ cell (T cell) percentage and HC50 were determined the following day after withdrawal.It showed that Ying Ji Su enhanced the phagocytic function of abdominal macrophages (t inspection P<0.01),increased the number of T lymphocytes in the peripheral blood (t inspection 0.01<P<0.05),and improved serum antibody levels (t inspection P<0.01).It was concluded that Chinese herbal additive could significantly enhance both specific and non specific immune functions of the body.
Key words:  Chinese herbal additive  anti-allergic reaction  immunopharmacology