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IFN-γ在大鼠胸段脊髓内的分布
胡 格1, 欧阳五庆1, 杨增岐1
西北农林科技大学 畜牧兽医学院
摘要:
为进一步探讨免疫-神经-内分泌三大系统之间的关系,用免疫组织化学SP法,对大鼠胸段脊髓内IFN-γ样免疫反应产物的分布进行了研究。结果表明,IFN-γ样免疫反应产物广泛分布于胸段脊髓各板层。其中背角Ⅰ、Ⅱ、Ⅲ层,胸髓中间带外侧核,腹角Ⅸ层内可见到较高密度的阳性胞体和树突。中间带和腹角内的阳性胞体的树突还伸向外侧索和腹索,有时可达脊髓边缘。
关键词:  IFN-γ  胸段脊髓  免疫-神经-内分泌网络  免疫组织化学SP法  大鼠
DOI:
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基金项目:国家自然科学基金资助项目(39770557)
Distribution of IFN-
Abstract:
For further study on the correlation of the immunology,nerve and endocrine,the IFN-γ immunoreactive structures in the spinal cord of rat were studied by using the technique of immunohistochemistry SP.The results indicate that:IFN-γ immunoreactive structures were widely distributed in thoracic the spinal cord.The IFN-γ immunoreeactive cells and dendrites with higher density were detected in the Ⅰ,Ⅱ and Ⅲ layer of whole spinal cord,the thoracic intermediolateral nucleus,the Ⅸ layer of ventral horn.The immunoreactive dendrite of intermedial and ventral horn extend to the lateral and ventral trace,some to the verge of spinal cord.
Key words:  IFN-γ  spinal cord  I-N-EN  immunohistochemistry SP  rat