| 摘要: |
| 神经视蛋白（OPN5）是非视觉成像视蛋白的重要成员之一，是可以感受紫外光的一种丝氨酸蛋白酶，能够介导光信号传输并引起节律相位的漂移。OPN5具有参与调控生物节律、动物繁殖、神经元生长发育、突触可塑性、记忆获得以及介导皮肤光信号转导等功能。文章综述了OPN5基因的结构与分布、生物学功能及其作用机制的研究现状，最后对其将来研究方向进行了展望。 |
| 关键词: 神经视蛋白 生物节律 动物繁殖 突触可塑性 记忆 |
| DOI： |
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| 基金项目:国家自然科学基金项目（31201798）；四川农业大学大学生科研兴趣培养计划项目（2014016） |
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| Progress in structure and biological functions of neuropsin |
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ZHANG Lei,KANG Bo,JIANG Dong-mei,et al
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| Abstract: |
| Neuropsin (OPN5) is a vital member of animal’s non visual opsin.OPN5 is a serine protease and an Ultraviolet sensor.It mediates the process of the optical signal transmission and causes the rhythm phase to drift.In recent years,significant progresses have been made on OPN5 function,particularly in the regulation of biological rhythms,animal reproduction,neuronal development,synaptic plasticity,memory acquisition and function mediating signal transduction in epidermal skin to serve as photoreceptors.In this paper,recent researches on gene structure,biological function and action mechanisms of OPN5 were reviewed. |
| Key words: neuropsin biological rhythm animal reproduction synaptic plasticity memory |
