摘要: |
通过对运动训练大鼠在安静状态、非力竭运动状态及力竭运动状态下脑组织超氧化物歧化酶(T-SOD)、铜锌超氧化物歧化酶(CuZn-SOD)、过氧化氧酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)活性及丙二醛(MDA)含量的测定,研究了槲皮素对运动训练大鼠脑组织自由基代谢及运动能力的影响。结果表明。服用槲皮素的运动训练组大鼠力竭运动时间明显高于力竭对照组(P<0.05);服用槲皮素的运动训练组及运动力竭组大鼠脑组织T-SOD,CuZn-SOD,CAT和GSH-Px活性均高于其相应的对照组,MDA含量低于其相应的对照组(P<0.05)。这表明槲皮素是一种有效的自由基清除剂,可减轻运动后因脂质过氧化而产生的自由基对机体的损伤,保护细胞膜的完整性,具有增强氧化酶活力和提高大鼠运动能力的作用。 |
关键词: 槲皮素 大鼠 自由基代谢 运动能力 |
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基金项目:陕西省自然科学基金项目(2003C137) |
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Effect of quercetin on exercise performance and free radical metabolism in brain tissue of trained rats |
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Abstract: |
The activities of T-SOD,CuZn-SOD,GSH-Px and CAT as well as MDA content in rats brain tissue are measured respectivety in sedentary status,exercise training status and exhaustive exercise status.The results show that the exercising time of rats taken the quercetin was much longer than that of the control rats.The activities of T-SOD,Cu-Zn-SOD,CAT GSH-Px were evidently higher in quercetin group than in control group while the content of MDA was lower.Quercetin has a strong action on enhancing anti-oxidative,clearing the free radicals and modulating the body endocrine system.It can relieve some bad effects of the intensity endurance exercise on the body and promote the capability of exercise. |
Key words: quercetin rat free radical exercise performance |