| 摘要: |
| 对烯二炔类、糖肽类、蒽环类、苯并二吡咯类、核苷类、β-内酰胺类、苯醌类等7类抗肿瘤抗生素的研究开发、作用机制、药效及临床应用现状进行了综述，提出今后抗肿瘤抗生素的研究应在新的分子靶点寻找、前药研究、多药耐药性克服等方面有所加强。 |
| 关键词: 抗肿瘤抗生素 作用机制 药效 临床应用 分子靶点 |
| DOI： |
| 分类号: |
| 基金项目:国家自然科学基金项目（30270979）；陕西省自然科学基金项目（2003C119） |
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| Research development in Antitumor |
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| Abstract: |
| The paper reviewed the research of application,mechanism of effect,function and clinical application of 7 kinds of antitumors:enedinyes,glycopeptides,anthracene nucleus,coumarone dipyrroles,nucleosides,β-lactams and benzoquinones.The aspects of searching new molecule target,researching the pro-drug and multi-drug resistance should be strengthened in the research into antitumor in the future. |
| Key words: Antitumor mechanism of effect drug function clinical application molecule target |
