| 摘要: |
| 将岭南黄公母混合雏780羽按饲养试验要求分为13组，每组4个重复，每重复15羽，纳米硒和亚硒酸钠2种硒源分别以0.1，0.2，0.3，0.4，0.5和1.0 mg/kg 6个硒水平添加到基础日粮中，配制成12种试验日粮，以基础日粮为对照,研究纳米硒和亚硒酸钠对肉鸡生长、肝脏脱碘酶Ⅰ活性和血清甲状腺激素的影响。结果显示：（1）基础日粮组肝脏脱碘酶Ⅰ活性和血清T3水平显著低于2种硒源的各组硒添加水平(P<0.05)，T4水平显著高于2种硒源的各组硒添加水平(P<0.05)。（2）亚硒酸钠添加量在0.1 mg/kg时，肉鸡生长性能、肝脏脱碘酶Ⅰ活性、血清T3和T4趋于平台；添加量在0.3～1.0 mg/kg时，肉鸡生长性能随硒添加量的增加而下降；添加量在0.2～1.0 mg/kg时，肝脏脱碘酶Ⅰ活性和血清T3水平随硒添加量的增加而下降，T4水平随硒添加量的增加而上升；1.0 mg/kg硒添加水平的肉鸡生长性能显著低于0.2～0.4 mg/kg硒添加水平，肝脏脱碘酶Ⅰ活性和血清T3水平显著低于0.1～0.3 mg/kg硒添加水平(P<0.05)，血清T4水平显著高于0.1～0.3 mg/kg硒添加水平(P<0.05)。（3）纳米硒添加量在1.0 mg/kg时，肉鸡生长性能、肝脏脱碘酶Ⅰ活性和血清T3水平仍然保持在高峰平台，T4保持在低峰平台(P>0.05)。（4）硒源添加量在0.1～0.3 mg/kg时，亚硒酸钠和纳米硒对肉鸡生长性能的影响无显著差异(P>0.05)；硒源添加量在0.4～1.0 mg/kg时，纳米硒组肉鸡生长性能显著高于亚硒酸钠组(P<0.05)。硒源添加量在0.1～0.2 mg/kg时，2种硒源对脱碘酶Ⅰ活性、血清T3和T4的影响无显著差异(P>0.05)；硒源添加量在0.3～1.0 mg/kg时，纳米硒组肝脏脱碘酶Ⅰ活性和血清T3水平显著高于亚硒酸钠组(P<0.05)，血清T4水平显著低于亚硒酸钠组(P<0.05)。上述结果说明，纳米硒的Weinberg剂量－效应的最适剂量范围宽于亚硒酸钠。 |
| 关键词: 硒 脱碘酶Ⅰ 甲状腺激素 肉鸡 生长性能 |
| DOI： |
| 分类号: |
| 基金项目:浙江省自然科学基金资助项目(M303435)；浙江省教育厅资助项目(G20040390)；国际科学基金资助项目(B/3452-1) |
|
| Effect of Nano-selenium on growth performance,type-Ⅰ deiodinase in liver and serum thyroid hormones of broiler chicks |
|
|
| Abstract: |
| Seven hundred eighty Linen Yellow broiler chicks,1 d of age,were used to investigate the effects of nano elemental selenium (Nano-Se) or sodium selenite (Na2SeO3) on the growth performance and serum thyroid hormones.The chicks were allocated to 13 treatments,each of which had 4 pens,15 chicks per pen.The thirteen dietary treatments were basal diet only (containing 0.04 mg/kg Se),basal diet + 0.1,0.2,0.3,0.4,0.5,1.0 mg/kg Se as Na2SeO3 or Nano-Se,respectively.The results were as follows:(1) S-upplementation with Se increased (P<0.05) the activity of Type-Ⅰdeiodinase in liver and serum T3,and decreased (P<0.05) serum T4.(2) When Na2SeO3 was added to the diet,the growth performance,the activity of type-Ⅰdeiodinase and thyroid hormones came to the peak value at a concentration of 0.1 mg/kg.The growth performance decreased with the concentration of Se at a concentration range of 0.3-1.0 mg/kg.The activity of type-Ⅰdeiodinase and serum T3 decreased and serum T4 increased with the concentration of Se at a concentration range of 0.2-1.0 mg/kg.When 1.0 mg/kg Se was added to the diet,growth performance was lower (P<0.05) as compared with the addition of a concentration range of 0.2-0.4 mg/kg Se,and the activity of type-Ⅰdeiodinase and serum T3 were lower (P<0.05) and serum T4 was higher (P<0.05) as compared with the addition of a concentration range of 0.1-0.3 mg/kg Se.(3) When Nano-Se was added to the diet,the growth performance,the activity of type-Ⅰdeiodinase and thyroid hormones remained steady at the peak value even at a concentration of 1.0 mg/kg Se.(4) There was no difference in growth performance between the treatments of Nano-Se and Na2SeO3 when the added concentration of Se was 0.1-0.3 mg/kg.The chicks had better (P<0.05) growth performance at a concentration range of 0.4-1.0 mg/kg with Nano-Se with than with Na2SeO3.There was no difference in the activity of type-Ⅰdeiodinase and thyroid hormones between the treatments of Nano-Se and Na2SeO3 when the added concentration of Se was 0.1-0.2 mg/kg.The chicks had higher (P<0.05) activity of type-Ⅰdeiodinase and serum T3 and lower T4 at a concentration range of 0.3-1.0 mg/kg with Nano-Se than with Na2SeO3.The results implies that for the best concentration range of Weinberg curve,Nano-Se is more uidely applied than Na2SeO3. |
| Key words: selenium type-Ⅰdeiodinase thyroid hormones brolier chick growth performance |
