| 摘要: |
| 根据天然杀虫活性物质苦皮藤素Ⅴ分子结构含有C6OH的特点，采用常规方法合成了苦皮藤素Ⅴ的酯、酮及醚衍生物，其结构经1H-NMR确认。采用叶碟饲虫法，测定了合成衍生物对粘虫(Mythimna sepirata)的杀虫活性。结果表明，苦皮藤素Ⅴ、酯、醚衍生物的LD50值依次为197.86,156.43和17.86 μg/g，酮衍生物没有杀虫活性。 |
| 关键词: 苦皮藤素Ⅴ 衍生合成 杀虫活性 |
| DOI： |
| 分类号: |
| 基金项目:国家自然科学基金重点项目(30130130) |
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| Synthesis and bioactivities of celangulin Ⅴ derivatives |
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| Abstract: |
| Based on the character of celangulin Ⅴ molecule structure,acetylated,carbonylated and allyl ether derivatives of celangulin Ⅴ were designed and synthesized.Their structures were comfirmed by 1H-NMR.The results of bioassay showed that the LD50 value of celangulin Ⅴ,acetylated and allyl ether derivative against the 3rd instar Mythimna sepirata lavae was 197.86,156.43 and 17.86 μg/g,respectively,and that carbonylated derivative had no insecticidal activity. |
| Key words: celangulin Ⅴ derivative synthesis insecticidal activity |
