| 摘要: |
| 用毒害艾美耳球虫杨凌株(YLn)感染14日龄雏鸡,检测毒害艾美耳球虫的致病性及其对4种常用抗球虫药的敏感性。以最适抗球虫活性百分率、抗球虫指数、相对卵囊产量和病变记分减少率为指标,进行综合评定,其抗药程度分为无抗药性、轻度抗药性、中度抗药性和完全抗药性4个等级。结果表明,该虫株对雏鸡有很强的致病性,每羽鸡经口接种1×105个孢子化卵囊时,致死率达63.3%;该虫株对地克株利有完全抗药性,对马杜拉霉素有轻度抗药性,对氯羟吡啶和氯苯胍无抗药性。 |
| 关键词: 鸡 毒害艾美耳球虫 抗药性 致病性 抗球虫药 |
| DOI： |
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| 基金项目:西北农林科技大学科研专项资助项目 |
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| Study on the pathogenicity and drug resistance of Eimeria necatrix |
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| Abstract: |
| Chicken were inoculated with Eimeria necatrix Yangling strain（YLn）,the assay of pathogenicity and drug resistance of YLn were conducted.Four grades of the sensitivity of drugs,including sensitive（S）,light resistant（LR）,middle resistant（MR）and complete resistant（CR）,were assessed by anticoccidial index （ACI）,reduction of lesion scores（RLS）,relative oocysts production（ROP）and percent of optimum anticoccidial activity（POAA）.The experiment results revealed that the strain was high pathogenic,and its mortality to chicken can reach as high as 63.3% when chicken are inoculated with a dosage of 1×105 sporulated oocysts each bird.The strain was completely resistant to Diclazuril,ligh resistant to Maduramicin,sensitive to Clopidol and Robenidine. |
| Key words: chicken Eimeria necatrix drug resistance pathogenicity coccidiostat |
