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家畜胎盘生物活性物质的研究进展
刘泽隆1, 张 涌1
西北农业大学 动物科学与动物医学学院
摘要:
综述了胎盘产生的几种特异性活性物质,即TGF-β,CSF-1, IGF, PAG,库尼特型蛋白酶抑制剂, bCYP19及相关基因的作用时间、部位和作用机制,以及这些物质的研究前景。认为加深其研究以利于完善早期妊娠和分娩发动诊断、妊娠疾病诊治、体外受精、人工输精妊娠以及人类避孕技术。
关键词:  胎盘,生物活性物质,蛋白质,mRNA,基因
DOI:
分类号:S852.2
基金项目:农业部生产技术重点项目(95牧-01-04-01)
Advances in the Study of the Biological Activity Substances Produced by Livestock Placenta
Abstract:
In this paper, several kinds of regulatory peptides produced by placenta,such as TGF-β,CSF-1, IGF,PAG,Kunitz-type proteinase inhibitor, proteinase produced by CYP19 gene and CYP19 associated gene etc., are discussed.The peptides have a very important role not only in the regulation of the growth and function of placenta by paracrine and autocrine, but also in the regulation of fetal growth, development and maternal endocrine.
Key words:  placenta,growth factor,protein,mRNA,gene,