| 摘要: |
| １５只１０～１２月龄的健康罗丝鸡经人工感染ＮＤＶ（Ｆ48Ｅ8）后，以红细胞Ｃ3ｂ受体花环试验、红细胞免疫复合物花环试验、Ｅ1花环试验及反向Ｅ玫瑰花环试验测定其红细胞、Ｔ细胞免疫功能及外周血中可溶性ＣＤ2（sＣＤ2）含量的变化。结果表明，鸡感染ＮＤＶ后，在Ｃ3ｂ受体花环率、Ｅ1花环率不断下降的同时，外周血中，ＣＤ2含量持续上升导致６只鸡死亡；９只鸡在感染的中后期伴随着Ｃ3ｂ受体花环率及Ｅ1花环率的回升，sＳＤ2含量趋向正常水平而耐过。认为高含量。ＣＤ2不仅与Ｔ细胞免疫功能受抑制密切相关，还可能与红细胞免疫功能受抑有关。 |
| 关键词: 可溶性CD2新城疫，红细胞CR1花环试验，红细胞免疫复合物花环试验，反向E玫瑰花环试验 |
| DOI： |
| 分类号:S852.4 |
| 基金项目: |
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| Changes of Soluble CD2 Amount and Erythrocyte Immune Function in Chicken Artifcially Infected With NDV |
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| Abstract: |
| The changes of soluble CD2 amount in peripheral blood and immune
function of erythrocyte and T cell of 15 10～12 month-old chickens artificially infected
with NDV (F48E8) were detected using erythrocyte CR1 rosette test,erythrocyte immune
complexes rosette test,reverse E rosette test and Et rosette test.The result showed that
after affected,6 chickens died off because of the continuous increase of soluble CD2
amount in peripheral blood with the decrease of the rate of erythrocyte CR1 rosette and
Et rosette;in the middle and late periods of infection,with the gradual recover of the rate
of erythrocyte CR1 rosette and Et rosette,9 chickens survived and the soluble CD2
amount tented to reach the normal level.The author believe that the high soluble CD2
amount is not only closely related with the immune funetion of T cell but also with the
restricted erythocyte immune function. |
| Key words: soluble CD2,NDV,erythrocyte CR1 rosette test,erythrocyte immune complexes rosette test,reverse E rosette test |
