摘要: |
用Danscher染色技术研究绵羊羔不同组织对中毒量硒的亲合性以及莫能菌素的影响。结果表明:该技术适用于研究硒中毒绵羊组织器官中的硒分布与组织病理学变化之间的关系,特别是对那些用常规染色法不呈现特异性或很小变化的组织如辅助淋巴组织生发中心、心肌传导纤维、胰岛及胰腺细胞、肝及肾小管细胞等有明显的优越性;组织中硒的分布和密度与损伤程度呈正比;同时服用安全剂量的莫能菌素能增强硒的毒性作用。 |
关键词: 绵羊羔,硒,莫能菌素,硒中毒,组织病理学,组织化学,组织染色 |
DOI: |
分类号:S858.266.9 |
基金项目: |
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The Affinity of Various Tissuses to the Toxic Doses of Selenium in Lambs |
Wang JianHua
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Abstract: |
Danscher's stahing techique was used to study the affinity of different tissues to the toxic doses of selenium and effects of monensin on it in lambs. Results showed that the Danscher's tachnique is useful in demonstrating the relationship between the distribution of selenium and histopathological changes within tissues,especially those tissues such as lymphoid cells in germinal centres of the secondary lymphoid tissue.conduction myofibres in the heart, liver and kindney cells,in which the gross and histopathological findings were non-specific or minimal.Concurrent administration of monensin sodium enhanced the toxicity of selenium. |
Key words: Lambs ,selenium,monensin,selenium intoxication ,histopathology , his-tochemistry ,tissue staining |